BDBM50063263 6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-phenanthridine::CHEMBL43355

SMILES CN1CCN(CC1)c1nc2ccccc2c2CCCCc12

InChI Key InChIKey=WLVCZYGIAIOYFH-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50063263   

Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063263(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-ph...)
Affinity DataKi:  0.0977nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063263(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-ph...)
Affinity DataKi:  0.230nMAssay Description:Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063263(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-ph...)
Affinity DataKi:  0.230nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063263(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-ph...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed